4. Omega-3 and depression
Research has suggested that a relative deficit in omega-3 fatty acids could predispose people to psychological disorders like depression. Some studies based on small quantities of individuals have also indicated that omega-3 supplements with high concentrations of EPA could help reduce depression symptoms in individuals who fail to respond to an initial treatment with antidepressants.
According to one study, using omega-3 supplements for treating major depression in individuals who don’t have anxiety disorders is effective. The study showed that omega-3 improved symptoms of depression in individuals with a depression diagnosis without an anxiety disorder. Effectiveness for these individuals was comparable to that usually seen with conventional treatment with antidepressants.
432 female and male individuals with major unipolar depression were enrolled for this double-blind, randomized study (neither researchers nor participants knew which capsules individuals received). For 8 weeks, half the individuals took OM3 Emotional Balance 3 capsules a day, a fish oil supplement which contains high EPA (eicosapentaenoic acid) concentrations. The other half took 3 identical placebo capsules containing fish oil flavoured sunflower oil.
In contrast to typically designed clinical studies for evaluating antidepressant effectiveness, a large proportion of individuals with complex and difficult-to-treat conditions were included in this study, as well as individuals resistant to conventional treatment with antidepressants and individuals who suffered from an anxiety disorder. The goal was to evaluate the value of supplementation with Omega-3 in a group of people more like those receiving outpatient clinic treatment.
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